Gene expression of ectopic thyroids

Gene expression of ectopic thyroids

Abu-Khudir R, Paquette J, Lefort A, Libert F, Chanoine JP, Vassart G, Deladoëy J. Transcriptome, Methylome and Genomic Variations Analysis of Ectopic Thyroid Glands. PLoS ONE 2010; 5(10): e13420 Highlighted by the Target Intelligence Service (TIS), a database used by pharmaceutical companies to identify groundbreaking research of relevance for their own work on potential drug … Continue reading »

Brain-Lung-Thyroid Syndrome

Brain-Lung-Thyroid Syndrome

Maquet E, Costagliola S, Parma J, Christophe-Hobertus C, Oligny LL, Fournet JC, Robitaille Y, Vuissoz JM, Payot A, Laberge S, Vassart G, Van Vliet G, Deladoëy J. Lethal respiratory failure and mild primary hypothyroidism in a term girl with a de novo heterozygous mutation in the TITF1/NKX2.1 gene. J Clin Endocrinol Metab 2009; 94: 197-203. … Continue reading »

a mutation in TPO

a mutation in TPO

Deladoëy J, Pfarr N, Vuissoz JM, Parma J, Vassart G, Biesterfeld S, Pohlenz J, Van Vliet G. Pseudodominant inheritance of goitrous congenital hypothyroidism caused by TPO mutations: molecular and in silico studies. J Clin Endocrinol Metab 2008; 93: 627-633. We reported a pedigree presenting with pseudodominant goitrous CH due to segregation of three different TPO … Continue reading »

Congenital malformation of the thyroid gland is not an environmental disease

Congenital malformation of the thyroid gland is not an environmental disease

Deladoëy J, Bélanger N, Van Vliet G. Random Variability in Congenital Hypothyroidism from Thyroid Dysgenesis over 16 years in Quebec. J Clin Endocrinol Metab 2007; 92: 3158-3161. Cited in the Yearbook of Pediatric Endocrinology 2008 (Karger). Only random variability was observed in the monthly and yearly incidences of congenital hypothyroidism from thyroid dysgenesis (CHTD) over … Continue reading »