calitonin cells where you don’t except them !!!

calitonin cells where you don’t except them !!!

Vandernoot I, Sartelet H, Abu-Khudir R, Chanoine JP, Deladoëy J. Evidence for calcitonin-producing cells in human lingual thyroids. J Clin Endocrinol Metab 2012; 97: 951-956. A lingual thyroid results from the failure of the thyroid precursor cells to migrate from the primordial pharynx to the anterior part of the neck. Fusion of the ultimobranchial bodies … Continue reading »

Fetal Goiter

Fetal Goiter

Stoppa-Vaucher S, Van Vliet G, Deladoëy J. Discovery of a fetal goiter on prenatal ultrasound in women treated for Graves’ disease: First, do not harm. Thyroid 2011; 21: 931. This article reports on the monitoring of a pregnant woman whose 19-week-old fetus presented a goiter revealed by ultrasound. The mother’s thyroid function was normal, whereas … Continue reading »

congenital hypothyroidism: becoming more frequent ?

congenital hypothyroidism: becoming more frequent ?

Deladoëy J, Ruel J, Giguère Y, Van Vliet G. Is the incidence of congenital hypothyroidism really increasing? A 20-year retrospective population-based study in Québec. J Clin Endocrinol Metab 2011; 96: 2422–2429. Highlighted by an editorial (J Clin Endocrinol Metab 2011; 96: 2395–2397). Induced a change in screening protocol in Quebec (higher threshold for 2nd test … Continue reading »

a mutation in TPO

a mutation in TPO

Deladoëy J, Pfarr N, Vuissoz JM, Parma J, Vassart G, Biesterfeld S, Pohlenz J, Van Vliet G. Pseudodominant inheritance of goitrous congenital hypothyroidism caused by TPO mutations: molecular and in silico studies. J Clin Endocrinol Metab 2008; 93: 627-633. We reported a pedigree presenting with pseudodominant goitrous CH due to segregation of three different TPO … Continue reading »